He called Michelle Obama's work with children “uninspired” and “ineffectual.”
The quotes come from an op-ed about childhood obesity that El-Sayed wrote in 2010.5 The ad deliberately misquotes him. As a public health expert, El-Sayed said that “America's political leadership” as a whole had been “uninspired” in addressing the obesity crisis among children. He then discussed Obama's “Let's Move” campaign as one of the few efforts to tackle the problem, calling the program “commendable, if ineffectual.”
His point was that “Let's Move” had failed to reduce childhood obesity rates, which is true.6 He praised Obama's work, writing that “to her credit, Obama has attempted to tackle the issue in a non-partisan manner.” But he said the program was flawed, since it emphasized individual choices over structural factors like access to healthy foods.
That's it. That's all he said. He mildly critiqued a program — not the woman who ran it — after praising it. Read the article yourself and see whether “disrespecting women” is a fair way to describe it.